Chemistry

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Brown, G .; Hughes, P. J .; Michell, R. H. (2003):Cell differentiation and proliferation - simultaneous but independent?. In: Exp.Cell Res.. 291, 282-288Campbell, K. H .; Alberio, R. (2003):Reprogramming the genome: role of the cell cycle. In: Reprod. Suppl.. 61, 477-494Crews, C. M .; Shotwell, J. B. (2003):Small molecule inhibitors of the cell cycle: an overview. In: Prog. Cell Cycle Res.. 5, 125-133De Veylder, L .; Joubes, J .; Inze, D. (2003):Plant cell cycle transitions. In: Curr. Opin. Plant Biol.. 6(6), 536-543
Title of the article
Plant cell cycle transitions
Abstract
Three decades have passed since the first recognition of restriction checkpoints in the plant cell cycle. Although many core cell cycle genes have been cloned, the mechanisms that control the G1-> S and G2-> M transitions in plants have only recently started to be understood . The cyclin-dependent kinases (CDKs) play a central role in the regulation of the cell cycle, and the activity of these kinases is steered by regulatory subunits, the cyclins. The activities of CDK-cyclin complexes are further controlled by an intricate panoply of monitoring mechanisms, which result in oscillating CDK activity during the division cycle. These fluctuations trigger transitions between the different stages of the cell cycle.
Dewitte, W .; Murray, J. A. (2003):The plant cell cycle. In: Annu. Rev. 54, 235-264Kai, M .; Wang, T. S. (2003):Checkpoint responses to replication stalling: inducing tolerance and preventing mutagenesis. In: Mutat. Res.. 532, 59-73Laiho, M .; Latonen, L. (2003):Cell cycle control, DNA damage checkpoints and cancer. In: Ann. Med.. 35, 391-397Malumbres, M .; Hunt, S. L .; Sotillo, R .; Martin, J .; Odajima, J .; Martin, A .; Dubus, P .; Ortega, S .; Barbacid, M. (2003):Driving the cell cycle to cancer. In: Adv. Exp. Med. Biol.. 532, 1-11Malumbres, M .; Carnero, A. (2003):Cell cycle deregulation: a common motif in cancer. 5, 5-18McGowan, C. H. (2003):Regulation of the eukaryotic cell cycle. 5, 1-4Park, M. T .; Lee, S. J. (2003):Cell cycle and cancer. In: J. Biochem. Mole. 36, 60-65Takuwa, N .; Takuwa, Y. (2001):Regulation of cell cycle molecules by the Ras effector system. In: Mol. Cell Endocrinol.. 177, 25-33Tyson, J. J .; Csikasz-Nagy, A .; Novak, B. (2002):The dynamics of cell cycle regulation. In: Bioessays. 24, 1095-1109Vermeulen, K .; Van Bockstaele, D. R .; Berneman, Z. N. (2003):The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. In: Cell Prolif.. 36, 131-149